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'Synthetic Minds', formerly known as the f(x)=e^x, serves as a mirror to the multifaceted, synthetic elements that are beginning to weave into the fabric of our society. Read the archive here.

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Synthetic Minds | The Race to Live Forever Has a Governance Problem

Harvard's David Sinclair just crossed a threshold: the first human trial of cellular reprogramming is underway. But the signal isn't whether we can reverse aging. It's that pension systems, billionaire capital, and authoritarian leaders are already restructuring around the assumption that we will.

Synthetic Minds | Google Maps for Cells Ends Trial-and-Error Biology

Cells aren’t spreadsheets; they’re cities. MIT’s multimodal AI disentangles what each measurement uniquely sees from the cell’s shared state—“Google Maps for cells.” This pushes R&D from trial-and-error to simulation-first biology, with ethics that must scale fast.

Synthetic Minds | The Tokenization of Human Perception

EgoX proves the metaverse isn’t a place you visit; it’s a layer reconstructed from existing footage. We’re moving from video to contextual space—spatial twins on demand. The risk: first-person realism makes hallucinations feel admissible. Verification becomes strategy.

Synthetic Minds | The Great Firewall, Now for Finance

China didn’t “ban crypto.” It built a gated bridge for money. Document 42 lets Chinese assets be tokenized offshore under strict approvals, while the mainland stays locked down. The global blockchain dream is splintering into jurisdiction-led ledgers.

Synthetic Minds | SaaS Is “Dead”? The Market Just Made a Costly Mistake

AI agents can now stitch workflows and finish tasks, so investors are dumping seat-based SaaS like it’s obsolete. That’s a category error. Real SaaS isn’t code—it’s years of domain decisions, compliance, edge cases, and accountability. Seats shrink. Outcomes win.

Synthetic Minds | Rare-Earth Freedom: When AI Rewrites Geopolitics

UNH used AI to turn decades of magnet experiments into a 67,573-compound database, then trained models to predict magnetism and heat tolerance. The result: 25 high-temp candidates that could reduce reliance on neodymium—reshaping EVs and far more than EVs.

Synthetic Minds | CRISPR Turns Superbugs Into Editable Software

Antibiotics lost because bacteria evolve faster than chemistry. UC San Diego’s CRISPR “search-and-replace” spreads through bacterial communities, deletes resistance plasmids, and restores sensitivity, even in biofilms. Synthetic biology is becoming a code editor for nature.

Synthetic Minds | Exo-Computing: When Intelligence Leaves the Grid

Alphabet just financed AI like a century-long utility; SpaceX is trying to run AI above the grid entirely. If orbital data centers become real, terrestrial hyperscale risks stranded capex and utilities lose anchor tenants. Exo-Computing makes judgment—not compute—the scarce asset.

Synthetic Minds | Smart Money: When Wall Street Learns to Speak Code

Money still moves like it’s 1999. AI agents won’t tolerate that. Binance and Franklin Templeton quietly launched off-exchange collateral using tokenized money market fund shares—assets stay in custody, still earn yield, yet power trading in real time. De-coring begins.

Synthetic Minds | China's AI Wave Forces the West to Wake Up

China isn’t “catching up.” It’s shipping in sequence: Seedance 2.0 for creation, Doubao 2.0 for agentic workflows, and DeepSeek’s next model for coding. WIPO patents and Science publication data show the industrial base behind the pace. What gets rewritten first in your org?